Am J Clin Exp Obstet Gynecol 2013;1(1):43-46
Review Article
Mucinous neoplasms of the appendix and ovary: confusing terminology
and clinical impact
Phillip C Usera, Donna C Ferguson, Janiel M Cragun
Department of Pathology, University of Arizona College of Medicine, Tucson, AZ, USA; College of Medicine, University
of Arizona, Tucson, AZ, USA; Department of Obstetrics and Gynecology, University of Arizona, Tucson, AZ, USA; Arizona
Cancer Center, University of Arizona, Tucson, AZ, USA
Received October 16, 2013; Accepted November 17, 2013; Epub December 7, 2013; Published December 15, 2013
Abstract: Mucinous tumors may arise from a variety of anatomic locations; however, their clinical behavior varies
considerably depending on their origin. When mucinous tumors involve the abdominal cavity, it may lead to mucinous
ascites, clinically known as pseudomyxoma peritonei. While most cases are derived from the appendix, it may arise
from a mucinous tumor of the ovary. However, the biological potential of these lesions vary, which is reflected by their
recently updated classification schemes. This article is intended to clarify the different classifications of the mucinous
tumors derived from the appendix and those derived from the ovary, and to provide therapeutic guidance for clinicians.
This may facilitate better communication between pathologists and clinicians, and optimize therapeutic decision
making. (AJCEOG1310007).
Keywords: Pseudomyxoma peritonei, appendix, ovary, mucinous tumors
Address correspondence to: Dr. Phillip C Usera, Department of Pathology, University of Arizona College of Medicine,
Tucson, AZ, USA. Tel: 520-626-6830; E-mail: userapc@gmail.com
Review Article
Mucinous neoplasms of the appendix and ovary: confusing terminology
and clinical impact
Phillip C Usera, Donna C Ferguson, Janiel M Cragun
Department of Pathology, University of Arizona College of Medicine, Tucson, AZ, USA; College of Medicine, University
of Arizona, Tucson, AZ, USA; Department of Obstetrics and Gynecology, University of Arizona, Tucson, AZ, USA; Arizona
Cancer Center, University of Arizona, Tucson, AZ, USA
Received October 16, 2013; Accepted November 17, 2013; Epub December 7, 2013; Published December 15, 2013
Abstract: Mucinous tumors may arise from a variety of anatomic locations; however, their clinical behavior varies
considerably depending on their origin. When mucinous tumors involve the abdominal cavity, it may lead to mucinous
ascites, clinically known as pseudomyxoma peritonei. While most cases are derived from the appendix, it may arise
from a mucinous tumor of the ovary. However, the biological potential of these lesions vary, which is reflected by their
recently updated classification schemes. This article is intended to clarify the different classifications of the mucinous
tumors derived from the appendix and those derived from the ovary, and to provide therapeutic guidance for clinicians.
This may facilitate better communication between pathologists and clinicians, and optimize therapeutic decision
making. (AJCEOG1310007).
Keywords: Pseudomyxoma peritonei, appendix, ovary, mucinous tumors
Address correspondence to: Dr. Phillip C Usera, Department of Pathology, University of Arizona College of Medicine,
Tucson, AZ, USA. Tel: 520-626-6830; E-mail: userapc@gmail.com
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